Comment · Thu, July 9, 2020 · ND Owner
NMN stability
Original post in this thread
Socialfilterdvit · 5 points
Is all powder form of NMN unstable & basically worthless? I got a free jar from another vendor. I had a choice of several different supplements and before I picked the powder NMN I asked thier support team this very question. They told me that as long as I keep refrigerated it'll be ok. It's obviously going to get hot during shipping, I got it in 2 days but still. They also have no incentive to tell me one of thier products is garbage but I buy stuff from them that you guys don't carry and have had really good experiences with them. I decided to ask you because I always get the right info. Thanks
What they were answering
Socialfilterdvit · 1 points
Thanks. I plan on buying your tablets next time anyway but was just wondering. Also would stacking piperine help with absorption?
u/MisterYouAreSoDumb · ND Owner
No, NMN is not a substrate for P-glycoprotein, which is what piperine inhibits to improve absorption. NMN actually has its own transporter in the small intestine that it uses for absorption. It's a transporter that neither nicotinamide riboside nor niacinamide can use, too. So NMN can reach much better plasma levels because of that transporter. It's also why our enteric coating works so well. It is delivering the intact NMN right to the area of the GI tract where the NMN-specific transporters are located! Pretty cool!