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Comment · Wed, March 25, 2020

Is Chaga a 5AR inhibitor?

Original post in this thread

WeAreTheAperture · 2 points

Per the title, is Chaga a 5AR inhibitor? I'm looking for ways to boost immunity but had a really better experience with Reishi. got super weepy, demotivated and practically depressed.

What they were answering

gitfetchmorecoffee · 1 points

I was referring to this study, which analyzed properties of different extracts, Sorghum Bicolor extract showed a -54.71 5-ar enzyme inhibition, showing it actually increased the enzymes.

5α-Reductase type 1 inhibition of Oryza sativa bran extract prepared by
supercritical carbon dioxide fluid

https://www.researchgate.net/profile/Warintorn_Ruksiriwanich/publication/251603402_5a-Reductase_type_1_inhibition_of_Oryza_sativa_bran_extract_prepared_by_supercritical_carbon_dioxide_fluid/links/59fab9e9458515d20c7d86a5/5a-Reductase-type-1-inhibition-of-Oryza-sativa-bran-extract-prepared-by-supercritical-carbon-dioxide-fluid.pdf

There is a cool chart, showing the properties of various extracts in 3.4.2.7. The 5˛-reductase type 1 inhibition assay. Figure 1.

"The O. sativa and C. tinctorius crude extracts and fraction No. 4
of the O. sativa crude extract also exhibited marked 5AR inhibition
activity at 92.73 ± 6.91, 91.52 ± 7.69 and 90.89 ± 8.5% ofthe control,
respectively, while the S. bicolor crude extract and their fractions
showed the negative result which stimulated the production of
5-
-reductase enzyme. "

If you want to test this out for yourself, there is a product called Tri sugar shield, by life extension that contains S. Bicolor extract. From my own personal experience it definitly will counteract the antiandrogenic effects of a heavy 5ar inhibitory stack, and bring back th…

u/MisterYouAreSoDumb

I am confused. That is saying it is inhibiting 5-AR. That's what the mushrooms are doing, too. How would it counteract the 5-AR inhibiting effects of the mushrooms by doing the same thing?

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