Why doesn't Nootropics Depot and Real Mushrooms provide terpene % for lion's mane?

We are currently working on a lab buildout to be able to do this type of testing. The problem is a lack of validated methods and validated reference standards. Anyone can claim anything they want. Far more often than not those claims are not based in sound science, or are completely made up. Real ISO 17025 labs will not take on projects without a sound scientific basis behind the validity of their results. No legitimate lab is currently willing to quantify erinacines and hericenones in lion's mane, due to the lack of consensus on the methods and standards. Trust me, if there was one that I was confident in we would be doing it.

So where does that leave us? Well we can do all the legwork to create our own methods and standards, but that is an expensive, time-consuming, and difficult process. It also requires some very accurate and expensive machinery. This would be a UPLC and triple quad MS, or perhaps a GC-MS/MS. You would probably want to NMR to validate the identity, too. Once we have isolated and validated the identity of the erinacines and hericenones, we could then use them as reference standards to quantify them using other methodologies like HP-TLC with quantification. If Sigma or another company had reference standards we could buy, this would be a whole lot easier. Without those we have do to all the method development and validation to separate, identify, and quantify them using verified methodologies. It is something we are certainly going to do. It's just taking us some time to complete another expansion of our lab buildout, and to get the equipment necessary for us to start development of the methods. I am not going to make claims that I cannot back up with sound science. I cut a check for a UPLC last week, but the other machinery will take me some more time. A full Waters UPLC-MS/MS system retails for about $480,000.

As for other people currently making claims about the amount of erinacines and hericenones in their lion's mane, I would ask for proof. Show me the results and methods you are using to justify that claim. As it stands, there is none. It's only words and numbers on a page; words and numbers that are next to others that are complete BS if you know you are doing. However, I'm not going to get into all that at the moment. Let's just stick to the science. I ask anyone making claims about erinacines and hericenones, or total terpenes in their lion's mane product, to show me the results and methods used to reach those numbers. If they are legitimate, and based in sound science, there should be no fear in releasing those. Then we can analyze them and try to recreate the results.

Regarding selling the isolated terpenes, that could be a possibility down the line. However, they would be expensive, and they likely all work together to give the desired effects. So taking one or a few might not give all the desired effects. All the human clinical research on lion's mane has used whole fruiting body mushroom powder. So we can speculate as to what isolated compounds would do in humans, but the clinical research is all on whole mushroom powder. We can definitely postulate how they would work based off animal studies, but at the very least we need to be absolutely sure we are isolating the proper compounds. Up until this point, there are no validated and legitimate methods to do that. They are all ad-hoc in individual studies without validation. If someone has done the leg work that I don't know about, I'd welcome that science with open arms! I just need to see it.