Comment · Sat, October 6, 2018 · Natrium Health & Nootropics Depot
Ginsenoside Rb2 (from Panax Ginseng) alleviates liver fat accumulation by restoring autophagy via induction of SIRT1 and activation of AMPK (2017)
What they were answering
absentnn · 1 points
Very fascinating!
I was reading that the gut seems to have a pretty big effect too... and then there's the elusive "compound K."
https://pubs.acs.org/doi/abs/10.1021/acs.jafc.6b04848
"Following oral intake of Panax ginseng, major ginsenosides are metabolized to deglycosylated ginsenosides by gut microbiota before absorption into the blood. As the composition of gut microbiota varies between individuals, metabolic activities are significantly different"
u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot
That's what GS15-4 ginseng is meant to increase. That's a pre-metabolized extract that increases compound K, so it absorbs quicker and reaches higher peak plasma levels. Ginseng is really complex and cool!