Comment · Thu, May 31, 2018 · Ceretropic & Nootropics Depot
4'dimethylamino-7,8-dihydroxyflavone (4'-DMA-7,8-DHF)
Original post in this thread
voyager256 · 5 points
Any one tried it or knows vendors that consider selling it (/u/MisterYouAreSoDumb ?).
From wikipedia: "...possesses higher agonistic activity at TrkB, is significantly more potent than 7,8-DHF both in vitro and in vivo, and has a longer duration of action"
"The compound has been found to produce neuroprotective, neurogenic, and antidepressant-like effects in animals."
Here is wikipedia article of the original compound 7,8-DHF:
https://en.wikipedia.org/wiki/7,8-Dihydroxyflavone
On paper it's very promising
What they were answering
solipsist1212 · 1 points
also are you thinking by chance of any R7-like prodrugs, like 7,8-diacetoxyflavone or 7,8-dipropanoyloxyflavone?
Now that I come to think of it, couldn't you hybridize the two together to get a possibly even more potent analog? Like 4-dimethylamino-R7? Or 4-dimethylamino-7,8-diacetoxy-flavone? etc....
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
Not sure on pricing yet. Also, we are not going to offer anything currently in trials, or under patent. Too much risk there.