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Comment · Fri, April 28, 2017 · Ceretropic & Nootropics Depot

Why the lion's mane you're buying is probably bunk.

Original post in this thread

1337sh33p · 16 points

If you've spent any time around this sub's lion's mane threads, you'll have seen /u/realmushrooms warnings about products containing mycelium on grain and standardized to polysaccharides rather than beta-glucan.

While these are perfectly valid critiques, IMO this is only half the picture when evaluating lion's mane extract. Research indicates that it's at least equally important to use a product containing material extracted with ethanol (or certain other solvents). I've poured somewhat extensively through the extant research and failed to find a single positive result using water extract, ~~which it seems almost all products currently exclusively contain (including ND & realmushrooms).~~ (see edit)

Furthermore, Beta-glucans are not the 'active ingredients' of lion's mane as far as NGF is concerned (as is commonly claimed) but research indicates that this effect is due to hericenones (in the fruiting body) and erinacines (in the mycelium).

Addendum: While pulling up references for this post, I found a couple of rat studies on aqueous extracts, and while they do help neurons recover from injury, there was no inve…

What they were answering

Aldarund · 6 points

Soon - same time when a Half Life 3 will come? :)

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

Haha! You don't know how painful it is to have a bunch of cool new products, but not be allowed to sell them yet. The last year and a half has tested my patience significantly.

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