montelukast (Singulair) as a nootropic?

Hello,

I recently was prescribed montelukast as an attempt to address anosmia (loss of smell) which hasn't been alleviated by many treatments (capsaicin, countless intranasal steroids, etc.) and other sinus issues (congestion, etc.) likely related to a dust mite allergy exacerbated by the fact that our dryer is currently venting inside the house (hopefully fixed soon).

Due to the anti-inflammatory properties inherent in all leukotriene antagonists (such as montelukast), I was curious about its potential effects on neuroinflammation and whether it may act as a nootropic.

I ran across a study—though it is a rat study so I'm a bit skeptical—showing that montelukast exhibited antineuroinflammatory properies, along with all of the benefits such an action would be expected to confer. From the abstract:

Here we show that a 6-week treatment of young (4 months) and old (20 months) rats with montelukast, a marketed anti-asthmatic drug antagonizing leukotriene receptors, reduces neuroinflammation, elevates hippocampal neurogenesis and improves learning and memory in old animals.

Before rushing to experiment with this agent, know that montelu…