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Comment · Fri, August 19, 2016 · Ceretropic & Nootropics Depot

Alpha Lipoic Acid vs NA-R-ALA

Original post in this thread

bitcoinsfordalulz · 2 points

Regular ALA is available at a bargain price. Would there be any reason to buy NA-R-ALA over ALA? Mostly interested in the bodybuilding aspect.

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

There is ZERO reason to buy racemic ALA, and even less reason to buy regular R-ALA. Straight R-ALA has even worse bioavailability than racemic, and Na-R-ALA has much better bioavailability, peak plasma levels, and AUC than either of them. Na-R-ALA taken orally reaches the same levels as intravenous racemic ALA. Not to mention, the S-ALA in racemic competes for absorption and binding with the R-ALA, and pure R-ALA polymerizes at very low temperatures. So it is not stable. The sodium salt of R-ALA is vastly superior in every aspect.

The Plasma Pharmacokinetics of R-\(+\)-Lipoic Acid Administered as Sodium R-\(+\)-Lipoate to Healthy Human Subjects.

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