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Comment · Wed, June 15, 2016 · Ceretropic & Nootropics Depot

What compares to Fasoracetam in terms of anxiety and mood uplift?

Original post in this thread

EhOhEl · 10 points

Fasoracetam is the first racetam I've tried and I've been taking to for a month now along with alpha gpc and prescribed adderall.

I want to know if anyone has experienced Fasoracetam and other nootropics and found something similar but better.

I've noticed Faso makes me sorta more happy, and reduces the edge to adderall, also it almost seems like it gives me energy or motivation after a good nights sleep.

These effects are sort of subtle and short lived (like 2-3 hours, plus like almost a better rest of the day "glow" after it wears off) though and Faso is quite expensive.

So anyone have something similar? Would another racetam be the next best choice? Or is there something better?

What they were answering

homosuperiorr · 1 points

Okay, and it should be used with benzodiazepines? It would work this way? Theoretically if we would take clonazepam or alprazolam, they definitely bind to a1 and a5 GABA A subunit (I can't find anywhere how high the affinity is exactly but they bind there for sure) with MRK-016 or α5IA (α5 subunit antagonists), then the benzodiazepine we took would not induce memory and cognition problems? Or they would compete to this subunit? There is a way to create something like perfect super selective benzodiazepine? How to take benzodiazepines and don't fuck up memory and cognition?

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

It depends on how selective the α5IA antagonist is, and its relative affinities to the benzos you are taking. If it is very selective, and has a higher affinity than clonazepam or alprazolam, then it should ameliorate the memory effects.

I think there is certainly a way to create a better benzo. My late partner Jason was trying to do that. He had some cool ideas. Sadly it was too long ago for me to remember details about them.

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