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Comment · Sat, April 9, 2016 · Ceretropic & Nootropics Depot

Stability of peptides in propylene glycol

Original post in this thread

Bomb_Jack · 19 points

There was quite of a talking about preserving the stability/preventing the breakdown of peptides in a solution by using deionized water instead of the regular one, but what about propylene glycol?
Is a peptide stable in a 100%-solvent solution of propylene glycol (and maybe kept at low temps)?

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

It depends on the peptide and the pH of your solution. Why do you want it in PG? Peptides are going to be the most stable as a lyophilized powder in a sealed vial, then stored in the fridge (up to a year) or the freezer (a year or more). So if you want to store the peptides for long periods, just do it that way. Then you can make a solution of them when you are ready to use them.

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