Skip to content
MYASDArchive
Archive/r/Nootropics

Comment · Fri, February 19, 2016 · Ceretropic & Nootropics Depot

Lion's Mane Megadose

Original post in this thread

[deleted] · 21 points

So, I just wanted to briefly share my experience with mega dosing Lion's Mane since there's very little information about that out there.
So, since I've abused amphetamine quite heavily (due to addiction) over the past 2-3 years, I've been interested in anything that could help my brain heal. In order to achieve that goal, in addition to multivitamins, fish oils, and the likes, I've been also buying any and all nootropic substances that increase BDNF, NGF, and decrease neurotoxicity. Among substances that I use for that purpose are: memantine, tianepetine, noopept (although I reduced the intake of that substance due to memory issues it causes), and more sporadically (due to its price) Semax. All of these substances have been tremendously helpful to me, so I am always on the lookout for substances with similar properties. And, although I usually avoid so called herbal or traditional medicines (due to the snake oil aspect of a lot of these "medicines"), just a few weeks ago I've stumbled upon the relatively well researched Lion's Mane. According to wikipedia, research has demonstrated the following:

* Stimulated animal nerve cells.
* A double-blind, parallel-group, placebo-contro…

What they were answering

EthanJPA · 4 points

I've been using Nootropics Depot's lion's mane for about 2 months, daily (roughly 1g each morning, with a rare second dose in the evenings, sometimes), and have noticed similarly positive effects.

I've also struggled quite extensively with stimulant addictions of various kinds, and I would have to agree with you that Lion's Mane has significantly aided my stimulant cessation, while also seemingly contributing to changes in vision, energy, and wellbeing. It's worth noting, of course, that this is all subjective, but the effects specific to the Lion's Mane seem pretty clear cut to me.

Also, it's worth noting that i've been taking ND's previous Lion's Mane formulation ( http://nootropicsdepot.com/lions-mane-mushroom-50-50-10-1-extract/ ) but will likely switch to their new one when my current supply runs out.

/u/misteryouaresodumb Could you elucidate any specific differences between the two formulations from an extract composition, and/or subjective effect perspective?

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

The Nammex one uses only the fruiting bodies, and keeps all the mushroom material in. Our other one is a 50/50 water/ethanol extract, 10:1. So only the soluble compounds come over.

Other MYASD lines in this thread

Related in the archive

Commentr/NootropicsFeb 24, 2021

Nootropics Depot not posting negative review

So we had to deal with some pretty big lawsuits last year. I wish I could say that is new, but I deal with half a dozen lawsuits every year. I just settled one two days ago, in fact. I have two more I am dealing with rig

475Lion’s maneCordyceps
Commentr/NootropicsJun 11, 2024

ND is lying about their in house testing

Since you are spamming this everywhere, I will put a link with my response everywhere. https://www.reddit.com/r/NootropicsDepot/comments/1ddeb2x/yall_wanna_explain_dis/l84g7mw/ [Since many people don't have access to C

66Lion’s maneAshwagandha
Commentr/NootropicsJan 28, 2020

This is part of the wholesale price list for "Nammex", the supplier of mushroom powders that many companies repackage/encapsulate and sell for a huge profit margin

Replying to eclecticlove1 · So where do you get the powder for the 8:1 dual phase extract?

We have our own suppliers, just like we do for all our ND branded products. They make it to our specifications. Then we test them in our lab for ID, content, beta-glucans, heavy metals, and now residual solvent residues.

40Lion’s mane
Commentr/NootropicsApr 27, 2017

Why the lion's mane you're buying is probably bunk.

First off, our Lion's Mane is not a traditional water extract. The water is used to break down the chitin in the cell walls, but the entire mushroom material is kept in. So you don't lose anything that you would with a f

35Lion’s mane
Commentr/NootropicsDepotMar 12, 2025

Is ND done launching new products?

We are absolutely NOT done with new products. We are in the thick of development for a bunch of them. Some of them are just taking longer than expected to get perfect, so we have had a lull in releases. That's just becau

147Lion’s maneTongkat ali
Commentr/NootropicsAug 28, 2023

new research on the lion's mane

Replying to GeauxTiger · Maybe Im missing a step here, so this is specifically about hericene A, a compound in lions mane. But how much? How much hericene is there, they tested at 250mg, if Im taking 2gm o…

It's talking about N-de phenylethyl isohericerin (NDPIH) and hericene A. You are not getting much of either in most lion's mane products. You have to grow specific strains in a specific way to get high levels of these ac

29Lion’s mane