Skip to content

Comment · Wed, November 4, 2015 · Ceretropic & Nootropics Depot

Tianeptine Sodium dose once a day.

What they were answering

srubek · 1 points

Honestly I can't say for sure in terms of effects on mood (again, I take many 'noots,' not to mention I haven't kicked the Kratom habit yet), but if I'm judging it's therapeutic window by its effectiveness as a bronchodilator (which is my prime rationale for using it), then I can honestly aver that it works from about 9am to 4pm. So 7 hours. My liver is a busy bee, though. So it may have something to do with less resources/enzymes being available at any given time to metabolize it.

I guess I should experiment and try taking the sodium salt again (now that I have my steady noot regimen and not-so-fun Kratom habit) to see if the sulphate form really has a longer half-life with me, or if it's just an effect caused by my liver's 'busy state.'

I wouldn't even want to try that though because I hate the come-down I get from Tianeptine sodium. I feel like I can't breathe. It seems to have a bronchoconstricting come-down for me. So I can't promise that this experiment will happen any time soon.

edit: changed NTM to "not to mention" - I realize now, that's not a common acronym.

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

No worries. Regardless, it's interesting to hear your anecdote regarding the comedown from sodium. I've had a lot of people say the same thing to me.

Other MYASD lines in this thread

Related in the archive

Commentr/NootropicsFeb 7, 2026

The story behind the FDA raid of Nootropics Depot

Replying to ProperBeat · Priceplow is pretty biased guys Here's [a more objective description](https://www.justice.gov/usao-nh/pr/arizona-company-and-ceo-sentenced-illegal-distribution-tianeptine-and-othe

...continued... Now a little backstory here... we did sell tianeptine years prior. I explained it in the podcast, but I will reiterate some here. I went through a bad depression when I was younger, and almost took my li

25TianeptineKratom
Commentr/NootropicsNov 2, 2014

physiological opiate tolerance & dependence on Tianeptine?

It is a very mild μ-opioid agonist (Ki Human of 383±183 nM, and EC50 Human of 194±70 nM, and EC50 Mouse of 641±120 nM for G-protein activation). That is not its main mechanism of action, and only really comes into play i

12TianeptineKratom
Commentr/NootropicsJun 7, 2017

[META] Modafinil discussions should not be prohibited anymore. The hype around it has died down, and it is still one of the most effective and safest nootropics.

Replying to WhateverChomp · > Seriously, is there actually anything specific about modafinil that people here want to discuss? Everyone is rallying around the idea of discussing it, but nobody is actually giv

>If somebody wants to talk about any of these in the context of cognitive enhancement, then let them. We already do. They just have to message us about it, or we might see it in the logs ourselves and approve it manuall

9TianeptinePhenibutNoopeptModafinil
Commentr/NootropicsDec 23, 2014

Nootropics to stop Kratom use

I find that tapering the dosage down over the course of two weeks, then using Semax, Selank, and Tianeptine during the transition, makes getting off it easy. I used kratom 2-3 times per day for almost a year, and got off

6TianeptineSemaxSelankKratom
Commentr/NootropicsDec 19, 2014

Tianeptine abusers- Another reason your misuse may affect responsible consumers

Replying to deftware · I understand, I just don't see how that makes sense when alcohol, with it's virtually non-existent medical value, is used solely for getting high. Are these people not adults who l

I am not saying it is bad. I think we should all be able to choose what we do to our own bodies. However, using a very useful therapeutic substance like tianeptine for recreation, increases the risk that the FDA and DEA

5TianeptineDosingKratom
Commentr/NootropicsSep 18, 2014

Tianeptine abuse: a case report (2014)

Replying to midnightketoker · Damn, I've tried to be cautious with this stuff after plenty of reading, but I'd say just dropping $40 on the sublingual is enough to discourage daily use for me. It's not even tha

Just keep to the recommended dosages, and you will be fine. Some people cannot resist the urge to go higher. That is when problems happen. I am on tianeptine right now. It is a massive help with getting off kratom, whic

5TianeptineKratom