Comment · Tue, August 4, 2015 · Ceretropic

Has anyone attempted to extract bacopaside XII or synthesize it?

Original post in this thread

srubek · 14 points

Edit: changed bacopaside XII to bacopaside XI - my mistake

Excuse my naivete when it comes to reddit rules...I hope I don't mess something up. Please correct me if I'm wrong. Still learning.

Everyone seems to really like bacopa in the nootropic subreddit community...but all the extracts and powders that I can find seem to be standardized for bacosides, not bacopasides. And when I look at the wiki for brahmi, the only chemical reference that I can directly relate to its nootropic benefit seems to be bacopaside XI.

Again, please correct me if I'm wrong.

And I'm not suggesting that anyone should isolate and consume bacopaside XI in large amounts or anything, but I'm interested if anyone has tried to synthesize the molecule or knows of anyone who has. Or if that even makes sense...

Again, excuse my naivete.

I did find this, which I feel like...is maybe a step in the right direction:
http://www.nrcresearchpress.com/doi/abs/10.1139/v09-111?mobileUi=0&#.VcEWLJNViko

But alas, not much more.

I'm very intrigued by this Bacopaside, and by the mechanism & chemical constituents behind its nootropic & mood enhancing properties. Enlighten me, reddit?

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · Ceretropic

Yes, I have been looking into it for a long time. The issue is that all the bacosides are very complex molecules, and would be extremely difficult to synthesize. This is why higher potency extracts have been the go-to way to get them. Even the study you linked used a water/ethanol extract to get them.

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