Would it be correct to say that l-tryptophan is superior to 5-HTP for correcting serotonin deficiency (since 5-HTP bypasses natural rate limiting)?

Comment · Tue, March 10, 2015 · 2 pts

I always type out aromatic L-amino acid decarboxylase, since it not only converts 5-HTP to serotonin, but also L-DOPA to dopamine. That is a big part of the issue with taking 5-HTP long term, and is kind of lost when peo

Comment · Tue, March 10, 2015 · 5 pts

5-HTP will raise your brain serotonin levels faster than L-tryptophan, if you take a peripheral aromatic L-amino acid decarboxylase inhibitor, like EGCG. If you do not take one, then most of the serotonin will be made in

Comment · Tue, March 10, 2015 · 2 pts

Yep, it is a pretty big one. On that same token, have you seen anything that up-regulates AADC? I can't recall running into anything that does.

Comment · Sat, March 14, 2015 · 1 pts

I'd say a few weeks, depending on dosage.

Comment · Thu, April 16, 2015 · 1 pts

Sure, some antipsychotics increase the expression of TPH. However, you have to determine why you want to up-regulate TPH. Up-regulation of TPH in the lower brain stem is actually positively correlated with depression. So

Comment · Thu, April 16, 2015 · 2 pts

Have you done 23andMe testing, to see if you have some mutations that affect your serotonin turnover?

Comment · Thu, April 16, 2015 · 2 pts

Yeah, and Prometheus. It will give you a good idea of why you might be responding well to certain supplements.