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Comment · Thu, March 26, 2015 · Ceretropic

Vaping nicotine vs nicotine gum

Original post in this thread

DeltruS · 17 points

Hello guys, I am having great results with nicotine gum. It gives me better wakefulness, motivation and memory. It also makes me feel more relaxed in a strange way, like I could just keep looking at something chilling out or learning, without feeling angst.

Comparing it with coffee, coffee increases heart rate too much, makes me sweat, gives me anxiety, makes sleep less good. But coffee is great for just thinking. Nicotine may give me slight anxiety too but I'm not too sure.

I've heard that:

- Vaping is more addictive because the onset of pleasure is almost instant, so the brain associates pleasure with the drug more easily.

- Vaping gives like 10-20x more nicotine than gum.

I am wondering:

- For people that have tried both, is there a difference in nootropic / stimulant effect? There must be with such a large increase in dosage, right? How do the effects scale? ie. Does the memory increasing aspect scale upwards while the stimulating aspect levels off? Or?

Because me vaping nicotine probably wouldn't be accepted by my family, I'm considering only taking it when I go out for a run / hike. Wouldn't it be interesting to be addicted to exercise because of this? Haha.

Ty for a…

What they were answering

DeltruS · 1 points

How do the pharmacodynamics of cytisine differ from nicotine? Does it hit different nicotinic acetylcholine receptor types? Also are you planning on releasing it?

edit: http://www.reddit.com/r/Nootropics/comments/2tua6n/cytisine_alternative_to_nicotine_with/
Found this thread, seems it has less effect on everything, except more effect on α4β2. This is cool because it seems to have less effect on the autonomic nervous system.

u/MisterYouAreSoDumb · Ceretropic

It's a partial agonist of the NACh receptors. It is much better tolerated than nicotine, with less side effects. It also does not seem to have the same reinforcing effects, nor any dependence. My girlfriend used it every day for months, then stopped cold turkey one day without any side effects or cravings. I used it to smooth things out when ceasing nicotine gum usage, and it made things very easy. It has been proven to be more effective for smoking cessation than nicotine replacement therapy. It's not as intense as nicotine can be, and does not seem to cause nausea like nicotine can.

Yes, we are about to release it as a solution.

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