Comment · Tue, December 23, 2014 · Ceretropic
Bromantane and NSI-189 interactions?
Original post in this thread
Debonaire_Death · 10 points
I have both an order of Bromantane (from AwakeBrain) and an order of NSI-189 freebase (from TLR) on the way to my house, and I am already very excited to see if the bromantane could give the NSI-189 more smoothness, direction, and consistent energy.
But I've tried NSI-189 before, and I know it can be nasty with drug interactions. Has anyone had experience mixing these two chemicals? Are there any logically derived reasons that they wouldn't work out together in my brain chemically?
What they were answering
Debonaire_Death · 1 points
So bromantane is anticholinergic? And ALCAR, Alpha GPC, these things will not help?
I thought you took cholinergic supplements with noots because nearly all nootropics are somewhat anticholinergic, and that simply upping acetylcholine concentrations will compensate for that in your brain.
So you are saying this isn't a viable recourse? Do you know of any ways to combat cholinergic antagonization? My mother is currently on Seroquel and it's been giving her wicked drymouth and insomnia; I gave her some Alpha GPC but, as you seem to suggest, it isn't doing much.
Is she just stuck with anticholinergic symptoms until she can get of of seroquel?
And I just combined fasoracetam (10mg) and bromantane (50mg). That leaves me concerned. Hopefully I won't be getting any anticholinergic side effects. I'll let you know if my body responds to Alpha GPC while I'm on bromantane.
u/MisterYouAreSoDumb · Ceretropic
I think you are confusing anticholinergic with choline uptake enhancement. Anticholinergic is when a substance blocks the effects of choline. Racetams enhance the uptake of choline into neurons, which means you are using more choline. They do not block the effects of choline.
Bromantane seems to only be anticholinergic at high dosages. Just keep the dosages reasonable, and it should be fine. However, there is no real way to combat the choline antagonism. You would need something to displace the Bromantane from the choline receptor.