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Comment · Wed, December 10, 2014 · Ceretropic

Article: Laughing all the way ... out of depression

Original post in this thread

aDepressiveRealist · 3 points

Thoughts?

Edit: Well, I either messed up or it didn't get linked for some reason. Ah well. Can't figure out how to edit the title, but angrysalad saved the day.

What they were answering

kanooker · 3 points

I think that /u/misteryouaresodumb posted once saying that nitrous oxide make have more permanent affect on b12.

u/MisterYouAreSoDumb · Ceretropic

Nitrous prevents the transmethylation of B12 by inhibiting methionine synthase. This means that even if you take regular cyanocobalamin, your body will not be able to use it. So supplementing methyl-B12 is a must. Also, SAMe would be a good one to add in if you are using NOS a lot.

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