Comment · Sat, September 6, 2014 · Ceretropic
9-fluorenol input
Original post in this thread
_julain · 9 points
I got a couple grams of 9-fluorenol two weeks ago and I've tried it a few times and I'd like to briefly share my experience. Also, let me preface this by saying I'm not your typical nootropics user I don't think.
The first time I took it (50mg first, 30mg two hours in) was after a weekend of crazy partying. I had maybe 2 hours of sleep that night and none the night before. I was feeling exhausted, but I wanted to test out just how much this would effect me in such a state. The answer was not much. I was happy about that. I went to sleep shortly after taking my second dose of 30mg. Slept fine.
The next day I had a lot of stuff to catch up on. When things pile up, I don't manage stress very well and I get anxious and tired and depressed. One way I can manage it is with the use of stimulants, though I'm avoiding those outside of recreation. So, I tried 50mg of 9-fluorenol. I can not believe how well it worked. Now, I felt like complete shit due to certain things I ingested over the weekend and I was very anxious in social situations, but that can be attributed to my own stupidity. That was perhaps the most productive day I've had in a year. It's almost like I could divert the st…
What they were answering
_julain · 1 points
Well I mean, it could be as simple as a dopamine antagonist on top of a 5ht6 agonist, no?
I did actually nap for two hours just now. Didn't intend on it, so maybe it's a bit of a heavier crash than I thought. Still, nowhere near as bad as real stimulants (as I would hope... it's hardly a stimulant in that sense).
I'm thinking you'd get some bounceback in a sense, maybe through 5ht6 upregulation or something. Not sure how long that would take, but some serotonin receptors downregulate notoriously fast so maybe the same goes the other way?
That'd just induce some bit of GABAergic response and less NE and DA release in the frontal cortex. Simply a "slowing down?" I hardly think the amount of dopamine release/left in the synapse by this stuff would be enough to have any noticeable effect directly on dopamine downregulation, at least that fast. So I'd think it would have to be strictly the 5ht6 response. Because this crash doesn't feel like a DRA or a DRI crash in the slightest. Not even a hint of it. Less "burnt" in a sense than a caffeine crash too. I've never felt a crash quite like it and I've felt a lot of crashes.
Also it's entirely possible modafinil would have the same crash if the half-life was the same.
u/MisterYouAreSoDumb · Ceretropic
It's for sure a crash with me. Some of our customers say they do not have any crash at all. I certainly do, though.
Jerrybusey just clued me into the possibility of a rebound effect due to an interaction with the orexin receptors. I had not known about orexin antagonists being used to treat narcolepsy. I am going to have to research this a little more.