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Comment · Thu, July 10, 2014 · Ceretropic

Nootropics mostly suck

Original post in this thread

AoE-Priest · 7 points

I'm by no means an expert in the area, but most of the research I've seen so far is done on old, demented stroked out grannies or done on rats. There is not much that is done on young, healthy people. The studies done on the young don't have the most robust methodologies either. And the studies tend to be inconsistent and show very modest effect sizes. Which if you've spent any time doing science you know it means most like the effect is BS and likely due to publication biases. The only things with convincing evidence seem to be caffeine, modafinil, and long-term use of bacopa. The absence of evidence is not evidence of absence, I will concede that.

Then there's the fact that nootropics, by their very nature, have a very robust placebo effect. So we can pretty much disregard all anecdotal reports that we see here. That leaves us with practically nothing to go on. Just venting, not trolling.

What they were answering

norepinephrinex · 2 points

For sure. I'm gonna have some fun with that last link you sent later...

So, having gone through the literature, you didn't find much in terms of phenylpiracetam on healthy individuals?

Given Russia is the originator of a good chunk of current cutting-edge noots, it'd be nice if we had a Russian well-versed in the field for an AMA... I'm kind of curious how things like PP and Noopept are viewed by the average person there, given my perception that one could purchase such things with the ease that an American buys a 5-Hour Energy.

u/MisterYouAreSoDumb · Ceretropic

There are some. It is for sure a good stimulant, and is banned by most competitive bodies; including the IOC. However, most of the studies deal with the stimulation and cold tolerance effects, rather than increasing memory of healthy individuals. I do not think I have any healthy human studies for phenyl that deal with memory enhancement. We have to go on anecdotes at the moment.

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I hope you like my last minute descriptions! It was my girlfriend's birthday this weekend, and my brother came into town. So I was a little rushed. Haha

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