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Comment · Thu, July 10, 2014 · Ceretropic

Nootropics mostly suck

Original post in this thread

AoE-Priest · 7 points

I'm by no means an expert in the area, but most of the research I've seen so far is done on old, demented stroked out grannies or done on rats. There is not much that is done on young, healthy people. The studies done on the young don't have the most robust methodologies either. And the studies tend to be inconsistent and show very modest effect sizes. Which if you've spent any time doing science you know it means most like the effect is BS and likely due to publication biases. The only things with convincing evidence seem to be caffeine, modafinil, and long-term use of bacopa. The absence of evidence is not evidence of absence, I will concede that.

Then there's the fact that nootropics, by their very nature, have a very robust placebo effect. So we can pretty much disregard all anecdotal reports that we see here. That leaves us with practically nothing to go on. Just venting, not trolling.

What they were answering

norepinephrinex · 3 points

Excited about the upcoming studies.

So I assume you've taken the trouble to look through some Russian database, translate the findings into something workable and then confirm that they haven't done any studies in healthy populations? Just want to confirm, since we both know none exist in the US.

u/MisterYouAreSoDumb · Ceretropic

Yes, I have access to translated Russian studies. I do not need to translate them, as most already are. You just need to know where to look. The Russians are more likely to test things for nootropic reasons than someone is the US is, due to the aforementioned flaws in our system.

Here's some reading for you, if you like:

SEMAX

Selank

Tianeptine

A fuckload more!

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