Comment · Thu, June 19, 2014 · Ceretropic
Vintage and off the radar nootropics / cognitive enhancers
Original post in this thread
baronjpetor · 17 points
Does anyone has experience with the following nootropics / cognitive enhancers:
Agomelatine (melatonin receptor agonist and a 5-HT2C receptor antagonist). In particular, how does it compare to melatonin ?
Amineptine (dopamine and norepinephrine reuptake inhibitor).
Nomifensine (dopamine and norepinephrine reuptake inhibitor)
JDTic (Kappa opioid antagonist)
Reboxetine (selective noradrenaline re-uptake inhibitor (SNRI))
These five compounds all seem to have interesting properties but they're not on our "map" for various reasons. Would be curious to hear more about them.
What they were answering
chemicalambrosia · 1 points
Yes, but how many cases were there? IIRC, it was still prescribed and available in other countries even after it was no longer available in France. How bad was it, really? Also, you receive hits if you search "tianeptine hepatotoxicity" as well:
http://www.ncbi.nlm.nih.gov/pubmed/7890892
I'm still interested in trying it.
u/MisterYouAreSoDumb · Ceretropic
From what I remember reading it was pretty bad. I think the cloroide group on the tricyclic ring structure in tianeptine protects from that issue.