Comment · Fri, February 14, 2014 · Ceretropic
Nitromemantine
Original post in this thread
sudojay · 4 points
There's an allegedly more effective and safer version of memantine called nitromemantine. All I've found is what's in this article but it seems pretty amazing. Does anyone know of a supplier or have any experience with this?
What they were answering
Smackugood · 3 points
What are eNMDA receptors exactly?
u/MisterYouAreSoDumb · Ceretropic
Extrasynaptic NMDA receptors. Alzheimer's patients have a higher number of eNMDA receptors than synaptic NMDA receptors, which causes excess electrical signaling. Since eNMDA receptors promote cell death, this kills neurons. The goal of nitromemantine is to selectively bind to the eNMDA receptors, and block their action. This allows the brain to heal itself, since it is not being overstimulated anymore.
eNMDA receptors are also implicated in other diseases like Huntington's, epilepsy, schizophrenia , etc.