Comment · Fri, December 27, 2013 · Ceretropic
"Glucose Is Not Willpower Fuel"
What they were answering
3AlarmLampscooter · 2 points
Hah, funny you should post that, I just edited my post talking about designing new amphetamine derivatives that especially don't target VMAT2. Solid advice. There are also a lot of other antioxidants in addition to CoQ10, ALA and ALCAR that are effective, but they are good ones.
Modafinil also greatly inhibits amphetamine induced DA release and acts as a DRI, so it has neuroprotective and anti-addictive properties much like selegiline, just through different pathways (the anti-addictive properties of selegiline on amphetamine are weaker than modafinil on amphetamine though).
I was personally not much of a methylphenidate fan, just too short acting and tweaky. I'm interested in trying some of the very potent modafinil-derived DRIs I identified in the longecity thread on high potency eugeroics. I also think Fluorenol warrants further exploration as the starting point for non-DRI eugeroics...
u/MisterYouAreSoDumb · Ceretropic
I agree, there are many other antioxidants that one can add. The old go-to vitamin C is a good one, as well as EGCG, vitamin E, and resveratrol. A good mix is best.
I have never tried methylphenidate, so I cannot comment on the subjective effects. It seems that some people love it, and some people hate it. That's either just personal preference, or their bodies actually react differently to it.
I do think that the new modafinil and amphetamine derivatives look interesting. It only makes sense to improve the molecules as we expand our understanding of the interactions between functional groups. Streamlining and improving the affinities, and reducing the ancillary side effects is going to lead to some very useful compounds.