Comment · Mon, November 11, 2013 · Ceretropic
5-HTP and multivitamins
Original post in this thread
dilnn760 · 5 points
So, I've read multiple articles on how taking 5-HTP with B6 metabolizes the 5-HTP too quickly, rendering it useless and potentially damaging the heart. I take multivitamins each morning, so my question is how long should I wait after taking the multivitamin to take 5-HTP to ensure that the B6 is out of my system enough that it doesnt metabolize too fast?
Im afraid that the only real solution is to switch to L-Tryptophan.
Also, very new to nootroopics and brain science, so go easy on me.
What they were answering
Guayusa · 1 points
Isn't a majority of serotonin found in your tummy anyways? I would imagine that B6 might convert it into a more bioavailable form, that would then get transported into the brain.
http://www.scientificamerican.com/article.cfm?id=gut-second-brain <-- for serotonin in the gut
http://jpet.aspetjournals.org/content/220/3/579.extract <-- done on rats, but what do you derive from their conclusions?
u/MisterYouAreSoDumb · Ceretropic
Peripheral serotonin cannot pass the blood brain barrier. Any conversion of 5-HTP to 5-HT in the periphery is useless to your brain.