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Comment · Mon, November 4, 2013 · Ceretropic

ELI5: Is there any danger related to Rhodiola's MAOI properties?

Original post in this thread

wpm · 12 points

Just started taking 500mg Rhodiola from Eclectic Institute. I had read some stuff way beyond my understanding from some older posts here, so I was wondering if someone could just clear it up succinctly. Thanks!

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · Ceretropic

Rhodiola does inhibit MAO-A and MAO-B, so caution should be taken when mixing it with catecholamine releasing substances. The most dangerous interaction would probably be from serotonin, as inhibiting MAO-A while taking a 5-HT releaser can lead to serotonin syndrome. Since it also inhibits MAO-B, you should also be careful with dopaminergic stimulants as well.

That being said, I have not personally experienced any issues while taking it and other stimulants. However, I never mixed it with strong ones like amphetamine.

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