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Comment · Wed, April 3, 2013 · Ceretropic

α-Tocotrienol Form of Vitamin E has Neuroprotective Properties

What they were answering

[deleted] · 2 points

First I should quote Wikipedia's page on antioxidants - it sets the stage quite well.
> The brain is uniquely vulnerable to oxidative injury, due to its high metabolic rate and elevated levels of polyunsaturated lipids, the target of lipid peroxidation.

ω3s are polyunsaturated fatty acids. In fact, DHA is found in extremely high concentrations in the brain.
From the abstract (emphasis added):

A growing body of research supports that members of the vitamin E family are not redundant with respect to their biological function. Palm oil derived from Elaeis guineensis represents the richest source of the lesser characterized vitamin E, α-tocotrienol. One of 8 naturally occurring and chemically distinct vitamin E analogs, α-tocotrienol possesses unique biological activity that is independent of its potent antioxidant capacity. Current developments in α-tocotrienol research demonstrate neuroprotective properties for the lipid-soluble vitamin in brain tissue rich in polyunsaturated fatty acids (PUFAs). Arachidonic acid (AA), one of the most abundant PUFAs of the central nervous system, is highly susceptible to oxidative metabolism under pathologic conditions. Cleaved from the membrane phospholipid bilayer by cytosolic phospholipase A2, AA is metabolized by both enzymatic and nonenzymatic pathways. **A number of neurodegenerative conditions in the human brain are associat…

u/MisterYouAreSoDumb · Ceretropic

Very cool! Adding α-Tocotrienol along side grape seed extract would be a nice antioxidant stack.

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