Comment · Mon, March 25, 2013 · Ceretropic
Is the antifertility effect of Bacopa in mice something you should be worried about?
Original post in this thread
[deleted] · 5 points
http://www.ncbi.nlm.nih.gov/pubmed/19041444
Mice of the Parkes (P) strain were orally administered Brahmi (250 mg/kg body weight/day, for 28 and 56 days), and effect of the treatment on reproductive organs and fertility was investigated.
In Brahmi-treated males, libido remained unaffected, but fertility was notably suppressed. The alterations caused in the above reproductive endpoints by the plant extract were reversible, and by 56 days of treatment withdrawal, the parameters recovered to control levels.
The dose is pretty high (250 mg/kg). You think it will noticeably affect fertility?
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · Ceretropic
250mg/kg in mice
250*4/37 = 27mg/kg in humans
That's 2.1 grams for my body weight. Not really that high.