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Comment · Wed, March 2, 2022 · ND Owner

Why does ND recommend such a high dose of their bacopa extract?

Original post in this thread

zidatris · 7 points

For context, given that their extract is pretty damn strong (>24% via HPLC/UPLC), why do they recommend up to 600 mg of their extract? Compared to, say, Synapsa bacopa, the recommended dose on that is 320 mg, which really comes out to around 120 mg if extract strength is accounted for (to compare apples to apples).

I’d love some input. Why that huge dose? Could that actually be beneficial in terms of bacopa benefits?

What they were answering

Direct reply to the original post — see the thread post above.

u/MisterYouAreSoDumb · ND Owner

Synapsa is patented, and as such we are under a TMLA, or trademark licensing agreement. For patented products, the patent holder often dictates what we can suggest for dosing. We are not under any restrictions for our own in-house products, though. Also, things don't always scale linearly in a simple way. Take tongkat ali for example. Our 10% extract has 5X the amount of eurycomanone as our 2%. However, we made the 10% tablets 100mg and the 2% 200mg. I set the dose based off our internal testing for what I felt was a solid dose of that specific extract, not to try and give an equivalent dose based on the % of actives. The same goes for our bacopa. A single dose of our 24% bacopa is solid for most people, but some might find better effects at 2 tablets a day. It just depends on the person.

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