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Comment · Thu, June 6, 2024 · ND Owner

MYSAD's Stack June 2024

Original post in this thread

tyham · 59 points

People ask occasionally what what u/MisterYouAreSoDumb is currently using. He posted earlier today: https://www.reddit.com/r/NootropicsDepot/comments/1d6b3nz/comment/l74o3rv/

* Infini-C
* Infini-B
* CoQSol-CF
* Yeast Extract
* D3/K2 (MK7)
* EGCG
* Andrographis
* Epicatechin
* CistaMAX
* Tongkat 10%
* HGW 10% & 50% together
* Hesperidin
* Berberine Phytosome
* Quercetin Phytosome
* Supercritical CO2 Boswellia
* Nicotinamide Riboside
* Reduced Glutathione
* 7,8-DHF
* Tiger Milk
* Cyanidin 3-Glucoside
* Micromag
* L-citrulline
* L-arginine
* GABA
* Smart PS
* Baikal Skullcap
* Sabroxy
* Maca
* Shoden
* Cognance
* Saffron
* L-theanine
* Taurine
* Sibelius Sage
* Supercritical Coriander
* Mushroom Magic Matcha Baller

---

* Relievex when I have soreness
* Tribugen & Eleuthero when I need a motivation boost
* Kanna and Isoliquiritigenin when I want a mood boost
* Ultra Concentrated Reishi before bed

What they were answering

12342ekd · -10 points

Sounds more like you got lazy and went for the easy, money making route. Do you realize that there’s a higher risk taking herbal extracts than synthetically created isolated compounds from the extract.

A herbal extract has unforeseen side effects due to the sheer amount of active compounds in them. It’s also hard to get anywhere with them since you can’t isolate a specific compound that’s helping you and figure out what works for your genetic makeup.

If you are thorough with the research chemicals you ingest - look at the mechanisms of action in the body, which are usually just a couple; look at all the human trials done on them, and if they're deemed extremely safe - then they will be safer, more effective, and have a cleaner result than a herbal extract.

u/MisterYouAreSoDumb · ND Owner

So the some people were in the room with us the whole time!

Easy money making route?!? Do you know the margins on synthetics and peptides? Some of these vendors have 95% profit margins. I know the cost of what they are selling. It's much much easier to sell the synthetics for crazy markups, to a crowd that is already looking for them, without many competitors selling the same thing, and doing no proper lab testing or quality control. It's literally easy mode for a business. The natural supplement market is one of the most competitive and difficult out there. You have billion dollar companies you are competing with, like Nestle or venture capital firms, that have budgets you can't even fathom and play dirty to keep market share. Margins are much thinner, and the overheads are higher. Lab testing is much much more difficult with complex matrices from botanicals or mushrooms. Then building out a stack of 10 ingredients increases that complexity and cost even further. As someone that has run both types of companies, a dietary supplement company is orders of magnitude more difficult and less profitable. If you want easy money, this industry is not it.

If you are thorough with the research chemicals you ingest - look at the mechanisms of action in the body, which are usually just a couple; look at all the human trials done on them, and if they're deemed extremely safe - then they will be safer, more effective, and have a cleaner result than a herbal extract.

LOL! Really, there are only a couple mechanisms?!? You clearly know pharmacology better than me! What are the couple mechanisms for bromantane? What about TAK-653? Tropisetron? Hell, even go for something that has been around for 50 years: piracetam. Can you fully explain all the mechanisms and subreceptors it hits? We haven't even fully elucidated the mechanism for ketamine yet. What about modafinil? If you know all the mechanisms of action it has, please publish your research so us lowly simpletons can learn from you! Shit, even lithium isn't fully understood. That's not even a molecule. It's just a chemical element that's been used for over a century. It was first prescribed in 1871 for mania, and we STILL don't fully understand its mechanism of action. You mention taking neboglamine. That's only been publicly known since 2005, and only has a handful of studies on it run by the pharmaceutical company developing it. You are going to try to convince me you know for a fact it is safe, effective, has a clean result and that you fully understand all its mechanisms? You are massively simplifying the science down.

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