Comment · Fri, April 29, 2022 · ND Owner
For people who didn't & did respond to -Epicatechin in regards to exercise benefits
Original post in this thread
Lightninghead · 15 points
When you trialed it how many hours before exercising did you take it, on average? what dose? & what effect did you find (positive/neutral/negative)?
I'm curious if the exercise benefits some people / studies report are gained from taking it far from exercise, vs being completely diminished or even hindering exercise adaptations when taken close to / after exercise. & if higher doses 200mg or above are actually detrimental rather than 100mg or 2x 50mg.
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https://www.frontiersin.org/articles/10.3389/fnut.2018.00132/
Surprisingly this human exercise study showed the epicatechin reduced exercise adaptations like vO2 max, 200mg over 4 weeks. different to promising mice studies & another human study i saw using 100mg (50mg x2 daily) which increased vO2 max.
Maybe as it has antioxidant/anti-inflammatory properties the problem was taking it in 2 100mg doses morning & evening too close to exercise. or 200mg is just too much for whatever reason.
\[time in plasma for 100mg in humans, it's mostly done by 4 hours with 100mg dose. (200mg doses last a bit longe…
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Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · ND Owner
It absolutely works for me to preserve muscle mass and reduce fat during periods of non lifting. I combine it with EGCG, NMN, hesperidin, and quercetin, and I preserve more lean muscle mass than I would without it. That being said, I have been way too busy to actually work out for quite some time. So perhaps it is better at keeping sedentary people from losing muscle mass than helping to build it in people that are lifting.