Comment · Thu, May 5, 2022 · ND Owner
For people who didn't & did respond to -Epicatechin in regards to exercise benefits
Original post in this thread
Lightninghead · 15 points
When you trialed it how many hours before exercising did you take it, on average? what dose? & what effect did you find (positive/neutral/negative)?
I'm curious if the exercise benefits some people / studies report are gained from taking it far from exercise, vs being completely diminished or even hindering exercise adaptations when taken close to / after exercise. & if higher doses 200mg or above are actually detrimental rather than 100mg or 2x 50mg.
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https://www.frontiersin.org/articles/10.3389/fnut.2018.00132/
Surprisingly this human exercise study showed the epicatechin reduced exercise adaptations like vO2 max, 200mg over 4 weeks. different to promising mice studies & another human study i saw using 100mg (50mg x2 daily) which increased vO2 max.
Maybe as it has antioxidant/anti-inflammatory properties the problem was taking it in 2 100mg doses morning & evening too close to exercise. or 200mg is just too much for whatever reason.
\[time in plasma for 100mg in humans, it's mostly done by 4 hours with 100mg dose. (200mg doses last a bit longe…
What they were answering
umbrella_term · 1 points
Is there any particular synergy you're going for when combining it with those?
u/MisterYouAreSoDumb · ND Owner
Just maintaining healthy weight while not losing muscles mass. A lot of it is driven by AMPK.