Comment · Tue, March 8, 2022 · ND Owner
What they were answering
wallyxii · 1 points
Do you think it stacks well with cerebrolysin??
I'm I'm loving cere but I'm also curious lately on tryin 7,8 dhf. If both are hitting bdnf or should be some next level neurogenesis lol
u/MisterYouAreSoDumb · ND Owner
Hard to say, as I have never combined them. However, Cerebrolysin hitting CNTF would go well with the BDNF/TrKb of 7,8-DHF on paper.
Comment · Wed, March 2, 2022 · 7 pts
Some people react really strongly to 7,8-DHF. For the people it works for, it can be pretty profound. It's hitting BDNF directly, which can give some people potent acute effects. As with everything, it really depends on
Comment · Wed, March 2, 2022 · 13 pts
BDNF is a growth factor, so it being correlated with cancer makes sense. That doesn't mean it is a causative factor. Cancer is out of control growth of mutated cells. They are still cells, though. So things that help the
Comment · Wed, March 9, 2022 · 5 pts
No way those small oral peptides are anywhere near IM Cerebrolysin or sub-Q P21.
Dude, you are tapering off benzos... Palpitations and chest pain are literally one of the most common side effects while tapering off benzos. Add a 5-HT2A PAM to the mix, and I can see why you might get that effect! You
Replying to janowski_d · u/MisterYouAreSoDumb any chance you can describe P21 and Orexin-A and how they affect you? I know basics of them, but still info is quite spare. Is Orexin-a worth trying on top o…
Here's the thing, I want to avoid giving my own anecdotes for a bit, to prevent confirmation bias. I don't want people seeing how I react, then convincing themselves they react the same way. I want people to try it thems
Replying to roleunplayed · Literally their subreddit. If u say otherwise the gas chamber is already piping
The year is 2150. MisterYouAreSoDumb has been dead for over 5 decades. The remnants of Reddit are run by the 4th generation of an advanced AI called ModGPT. As it turns out, they have become drunk with the sheer power th
Replying to Chargers95 · CNTF is the growth factor key in the survival of new neurons, correct? Edit: it’d be interesting if you guys could find a natural product that could increase CNTF similarly to P21…
Yes, CNTF is a crucial for the growth of astroglia. It's one of the critical neurotrophic factors in the brain. Many people focus on BDNF and NGF, but CNTF and GDNF are both crucial, too.
Replying to Silver-Interaction-2 · >CNTF What nootropics hit CNTF besides Cerebrolysin/P21?
[Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes](http://europepmc.org/articles/pmc4644097?pdf=render)
No!!!! You can't just say, "Ohh, the active sequence in P21 is DGGL, so let's just sell powdered DGGL!" Pharmacodynamics do not work like that! That would be like saying, "Ohh dopamine is good. Let's sell powdered dopami