Comment · Thu, September 30, 2021 · ND Owner

CDP-Choline and upregulating D2 dopamine receptors

Original post in this thread

Translation333 · 10 points

I've read that CDP-Choline upregulates D2 dopamine receptor, so does that mean that only CDP-Choline(Cognizin) upregulates D2 receptor or does Alpha-GPC or any choline source for that matter do the same thing? Sorry if the question seems silly

What they were answering

Translation333 · 1 points

u/MisterYouAreSoDumb can you help here with the answer

u/MisterYouAreSoDumb · ND Owner

/u/NootropicsDepotGuru's response above is exactly what I would say. It's the uridine content of CDP-choline that leads to the D2 up-regulation. Alpha-GPC and choline L-bitartrate don't have any uridine, so they would not have that effect. However, you can take uridine monophosphate or triacetyluridine alongside alpha-GPC for the best of both worlds.

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