Comment · Thu, August 5, 2021 · ND Owner
When will NMN be back in stock?
Original post in this thread
ozigiri · 21 points
Mostly what the title says… Been looking for it for weeks and nada
What they were answering
ebowden · 1 points
Are you planning on doing enteric coatings for the berberine tablets? The preponderance of papers would suggest that enteric coatings are simply the standard way to go if one wants high oral bioavailability, but I am having trouble tracking down specific sources.
Also here's some unrelated oral bioavailability stuff you may or may not have seen(including one that came out this year):
https://www.tandfonline.com/doi/full/10.1080/10717544.2017.1321062
https://www.sciencedirect.com/science/article/pii/S1319562X20304939
It would be interesting to see how these combined with oral bioavailability enhancing compounds, like the one you already use, silymarin.
u/MisterYouAreSoDumb · ND Owner
Berberine does not break down in stomach acid, so an enteric coating would be superfluous. Also, silymarin absorbs in the stomach. It is also gastroprotective when released in the stomach, so enteric coating it would remove some of the beneficial effects of the silymarin.