Comment · Mon, January 18, 2021 · ND Owner

Is 1:1 lions mane still worth it?

Original post in this thread

Kaia11 · 5 points

I want to buy from Nammex but their stock is empty for 8:1. Was wondering if 1:1 is still good aswell? For the supposed brain/mental benefits etc. Thank you

What they were answering

Kaia11 · 1 points

I read on a blog that the whole "ndf" and mood improvement is only from alchohol extract and not from hot water. Is that false or?

u/MisterYouAreSoDumb · ND Owner

Till recently, the only human clinical studies on lion's mane were with whole mushroom powder, not even an extract, much less an ethanol extract.

Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake

Improving effects of the mushroom Yamabushitake \(Hericium erinaceus\) on mild cognitive impairment: a double‐blind placebo‐controlled clinical trial

So those human clinical studies used what was effectively the same as our 1:1 lion's mane. The ethanol extract thing is an assumption based on in vitro and animal studies. I do think the 8:1 is more potent, and that is a dual water/ethanol extract. However, that does not mean the 1:1 doesn't work. We have human clinical studies showing lion's mane fruiting body powder works in humans, even with ZERO extraction.

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