Comment · Sat, November 7, 2020 · ND Owner
Fasoracetam and GABA-B receptors recovery
Original post in this thread
3ric843 · 19 points
Hello everyone,
I see that fasoracetam is marketed as a solution to help your gaba-B receptors recover by up-regulating them. Apparently it helps with withdrawal and lowers tolerance quickly, and repairs you GABA-B receptors.
This sound very interesting to someone like me, who abused gabaergics (phenibut, GHB and alcohol mainly, but also etizolam has been sometimes taken every night for sleep for some periods) in the past and is trying to recover.
But I also read that the up-regulation only lasts while you are supplementing, and there is a rebound when you stop, similar to the one GHB or phenibut does.
So my question is, anyone know if it is just a marketing gimmick?
From my understand, it's either:
1- A healthy person takes it, GABA-B up-regulates, after cessation everything comes back to normal
2- A person with damaged / downregulated GABA-B receptors takes it for a while, it fixes and upregulates its GABA-B receptors, after cessation there is some loss of up-regulation but it stays better than before the fasoracetam cycle
3- A person with damaged / downregulated GABA-B receptors takes it for a while, it upregulates his receptor, but after cessation, everything goes back…
What they were answering
bitmyneck · 1 points
Ok so, adeneylate cyclase. I digged I little into it for reducing adrenaline, cAMP etc... Didn't remember well how it work.
Will fasoracetam boost adrenaline or reduce it ?
u/MisterYouAreSoDumb · ND Owner
Adrenaline actually stimulates adenylate cyclase, not the other way around. So I am not sure how modulating adenylate cyclase would affect adrenaline, if it even would.