Comment · Wed, September 16, 2020 · ND Owner
Sleep support causing next morning depressed mood, pessimistic feelings questions....
Original post in this thread
Bigpoppapenguin123 · 13 points
This is a two part question. Any feedback is appreciated!
First off I love Nootropics Depot and all that you guys bring! Outstanding service! I had been experimenting with the Sleep Support without the zinc for a few weeks now. Admittedly, I am one of the reviewers on the website that left a review complaining about the Sleep Support causing some depressive feelings. A ND admin responded to my review and another’s regarding the same issue. They said that it’s possibly the bacopa in the stack that’s causing a increased production of serotonin, resulting in less dopamine which can be mitigated by taking l-tyrosine or NALT in the morning.
I took some NALT with P5P the mornings after, but I really didn’t notice an improvement. I just picked up some regular L-tyrosine, so I’ll try larger doses of this with P5P.
Question 1: Now, I was actually wondering if the negative effects I’m getting is NOT from the serotonin and dopamine balance being thrown off, but rather from and increase of ACETYLCHOLINE?? I know lemon balm, uridine, and bacopa have an influence on acetylcholine, but I’m not so sure about magnolia, the oleamide, or Shilajit. Do these last three increase acetylcholine to s…
What they were answering
Dihexa_Throwaway · 3 points
Yep. I was taking alpha gpc just fine for a few days, and, when I added shilajit, bam: 03 days of depression.
After that, I've researched it and found the same study you've posted; then, I came to the conclusion that shilajit was an acetylcholinesterase inhibitor. Even if shilajit has only a weak effect on acetylcholine, it is probably too much for my individual neurochemistry when alongside an acetylcholine precursor.
Of course, one could argue that alpha gpc was building in my system for a few days before taking shilajit, and that it was just a coincidence. But, I'm never adding those two to a stack ever again.
u/MisterYouAreSoDumb · ND Owner
I have to be VERY careful with alpha-GPC, or I get a 3 day depression, too. 150mg every other day is the most I can do.