Comment · Mon, October 29, 2018 · Natrium Health & Nootropics Depot
Adamax - The one that got away. Adalank?
Original post in this thread
Enkepharis · 9 points
If anyone was around to see the dying light of ceretropics final days in psychonaut exploration, you may have seen "adamax". Adamax is N-Acetyl-Semax-amidate with an extra special adamantane group to help abosrbtion. This means adamax is equipped to travel through any substance in your brain, fat and water. Which means it will disperse more widely through out. Its pretty interesting, and is proudly the child of MYASD's praisebetohiswisdom.
​
I recieved a quote for 100mgs of Adamax : $2350, with 1350 being unrefundable regardless of the result. Im waiting to hear back from 9\~ other companies for quotes.
perhaps I should only make this post when I have all the quotes, but boy I'm impatient.
I also thought about selank, and how it could also benefit from the adamantane group. It would be intense, despite being an anxiolytic.
These I consider to be God noots, not because of what they do on their own, but because any drug that induces hyperplasticity has ALOT of potential to be used with electrotherpies like tDCS and TBS. Long lasting improvements to working memory I hear you say?
Basically, I'm getting the word out for not only adamax, but Adalank.
Ther…
What they were answering
Direct reply to the original post — see the thread post above.
u/MisterYouAreSoDumb · Natrium Health & Nootropics Depot
I shake my head every time people think they are getting real P21, or any peptide made with that adamantane moiety. It took me years to get an amino acid lab to make it properly, and we had to modify the structure a bit to get the solid-phase peptide synthesis to work. The amino acid mentioned in the P21 study kept causing the peptide synth to fail. It needed to be modified a bit for the peptide synthesis to actually succeed. I never told anyone what modification we did, and the amino acid lab that did it for us had no idea what we were using it for. That did not stop some Chinese peptide labs from offering "P21" with alanine-glycine capping the C-terminus, since they got confused by my AG in the sequence we had listed. Then a bunch of our competitors started selling that fake P21, and even had the fucking mass spec up from the supplier with the wrong mass and wrong sequence... They did not even understand what they were looking at enough to know it was showing they were selling fake P21. Some of them STILL have that fucking wrong mass spec up to this day!
The $2,350 is actually pretty reasonable, since they are likely going to try synthesizing the adamantane moiety themselves. That's expensive. The synth will also fail in the end, most likely. Genscript might get it to work if they keep trying. We had one lab not give up, and they finally made it properly on their own. We got 15 MILLIGRAMS from that. Basically it was a reference standard for a few thousand dollars. Efficiently scaling that up to production sized batches is much more difficult. We still have a ton of that modified amino acid, and unless someone has stolen a bunch from us to use in their synths, or they have independently figured out what we did to modified it so that it would work, they are likely just selling you alanine-glycine capping the end.