Mk 677 Stock

Comment · Thu, April 14, 2016 · 8 pts

We had two batches come in from the main two labs making MK-677. They were only about 94% pure. We sent off to another lab for another opinion, and they ran it with UPLC, which is even more sensitive. They came to the sa

Comment · Fri, April 15, 2016 · 3 pts

It will still work fine. It will just be making you consume impurities. I cannot say how adversely that will affect you, as we don't know the exact impurities. I could mass spec it, and get a good idea. However, it's not

Comment · Fri, April 15, 2016 · 2 pts

Yeah, if either of these new synths turns out to be pure, I am going to buy it all.

Comment · Fri, April 15, 2016 · 3 pts

Yeah, there certainly could be. Benzyl chloroformate can be used as an intermediate in the synthesis of MK-677. Benzyl chloroformate becomes phosgene when exposed to water, which is a toxic gas. You certainly do not want

Comment · Tue, April 26, 2016 · 1 pts

That's not surprising. What was the vendor? Our new synth is shipping to us today. We will test it as soon as it comes in, and my team will be making a batch as fast as humanly possible once we confirm it is pure.

Comment · Thu, April 28, 2016 · 2 pts

I've never really heard of them. I'll make a note about their MK-677.

Comment · Thu, April 28, 2016 · 3 pts

That's no fun! Some of the compounds used in the synthesis of MK-677 are pretty nasty. If they put out a shitty synth, I could see the impurities causing some issues like that. That's why we are so strict with what we wi

Comment · Fri, April 29, 2016 · 1 pts

Yes, it's the mesylate salt. All MK-677 out there is the mescylate salt. We run FTIR for identity and HPLC for purity, and test it against a Sigma Aldrich reference standard. We even sent this last batch off to a 3rd par

Comment · Fri, May 6, 2016 · 5 pts

The new batch was just delivered! So after I answer my messages and emails, I'll head into the lab to analyze it. Cross your fingers! It certainly looks like a much better synth than the last few. So that is good.

Comment · Tue, May 10, 2016 · 4 pts

Yep, both of the new batches came in impure. They have a ton of benzyl chloroformate in them, which is a nasty toxin. Literally all batches of MK-677 we have received this year have been tainted with benzyl chloroformate

Comment · Mon, May 16, 2016 · 2 pts

Well every supplier screws up. This supplier that sent the 94% pure batch was the same supplier that sent the last over 99% one. That's why it's been so frustrating. If I could just stick to one supplier, and always be g

Comment · Mon, May 16, 2016 · 1 pts

Yeah, it is very stable in solution. It should be potent for at least 2 years, as long as it is kept out of the sun and high heat.