Comment · Sat, March 26, 2016
What they were answering
bigskymind · 1 points
I appreciate your knowledge in this area — do you think taking a 20-30mg test dose is wise for MDMA neophytes?
u/MisterYouAreSoDumb
Yes, taking a small initial dose of a new compound is always advisable. Alexander Shulgin did that with every new compound he investigated. It's better to be safe than sorry.
Comment · Fri, March 25, 2016 · 5 pts
[MDMA \(ecstasy\) pharmacokinetics in a CYP2D6 poor metaboliser and in nine CYP2D6 extensive metabolisers](https://mega.nz/#!xMJD1CDB!-80uy8qKs7MR-Pq4fLMmc0M1qYDJNxb-eCyT1g62YAM) >Evidence that individuals possessing a
Comment · Fri, March 25, 2016 · 7 pts
A real allergy is a hypersensitivity of one's immune system to a certain compound. It's an immune/inflammatory response to an exogenous substance. I would not consider being a poor metabolizer of something to be an aller
Comment · Fri, March 25, 2016 · 3 pts
Yeah, MDMA has been shown to disrupt mitochondrial function acutely. However, it returns to control levels within 24 hours. Taking some supplements that support the electron transport chain, like CoQ10, ALCAR, PQQ, etc.
Comment · Fri, March 25, 2016 · 3 pts
Modafinil actually increases mitochondrial membrane potential, and is neuroprotective in some cases.
Comment · Sat, March 26, 2016 · 2 pts
Yep, that is a good analogy. Lactose intolerance is an interesting subject on its own too. Your body produces the enzyme when you are young, and keeps doing it if exposure to lactose is consistent. However, if you stop
Ok, I did promise that I would make another post regarding supplementation to mitigate MDMA induced neurotoxicity. I have just been putting it off. Since my last post, I have gathered more information regarding my theory
This is probably going to be the first in a series of discussions I start about MDMA. There's just too much information for one post. Therefore, I am going to start with one that is very interesting to me: MDMA's metabol
Thank god. The harvesting of safrole was a massive cause of deforestation. Using a minuscule amount of petroleum is much more sustainable. This article is stupid. >MAPS did not comment on the infrastructure necessary t
Replying to Trance_Forming · /u/misteryouaresodumb
Yeah, a bunch of people have been messaging me about it. I have always said that I was putting my research out there to help people, and make the use of this amazing substance safer. The best way to do that is to get peo
Just so everyone is aware, there has never been a vaccine for ANY type of coronavirus. We have never successfully produced a coronavirus vaccine. So people holding out hope that we will have one to market anytime within
http://www.sciencedirect.com/science/article/pii/0024320584900948 >The results suggest that the elevations in brain 5HT and 5HIAA levels produced by caffeine do NOT enhanced 5HT synthesis, despite significant elevations