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Comment · Fri, February 26, 2016 · Ceretropic & Nootropics Depot

Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments.

What they were answering

ebowden · 2 points

Yes, the mice with BDNF over expression. Perhaps, though I'm REALLY going out on a limb here, it might be behind the brain volume loss from Valproic acid. I'd love to do research on it when I can.

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

It could very well be linked to the p75 neurotrophic receptor. Activation of that receptor can signal for a cell to undergo apoptosis.

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