Comment · Wed, January 13, 2016 · Ceretropic & Nootropics Depot
Is this dosage of Curcumin and piperine enough for the benefits?
What they were answering
shrillthrill · 2 points
be aware that curcumin 95% is not equivalent to the patented curcumin 95 (curcumin c3 complex) that has some studies behind it.....i made that mistake for awhile.....the c3 complex is a specific blend of curminoids, curcumin, and its oils
Yep, I'm aware. I was just curious to try it.
but i am pretty sure theracurmin is ineffective period as far as free curcumin absorption.
It has more research (and better quality) than longvida. The research says bioavailability is good, and reviews say their methodology is also good. I recommend reading this post I made about enhanced curcumin technologies. Note the mentioned problems with the quality of longvida research.
I made a comment with a key to the brand names.
/r/Nootropics/comments/3jlyso/beyond_yellow_curry_assessing_commercial_curcumin/
I hope longvida responds with funding independent high quality research, or independent research appears.
u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot
I actually went through all this research when you made the post a while back, which is what took me so long to decide on Longivda. The issue with the Theracumin research is that they do not separate out free curcumin from its metabolites. So the absorption numbers are skewed. It does not show the same high free curcumin levels in the blood that Longvida does, only high levels of metabolites. The issue with that is twofold. One, we don't know the effects of the metabolites in the periphery in comparison to free curcumin. It would seem from a few effectiveness studies that free curcumin is needed for it to be uptaked into the cells. This also plays into issue two: Theracumin has not been shown to penetrate the blood brain barrier like Longvida has. So even if it does show effectiveness in the periphery (still inconclusive), it is not going to reach the brain to affect Alzheimer's like the Longvida complex has been shown to do.
My other issue with the study you linked was who funded it: OmniActive Health Technologies.
FUNDING
Financial support was provided by OmniActive Health Technologies, Inc.
They are the ones making the CurcuWin curcumin product. They have a vested interest in downplaying the absorption of the competition. The Longvida section makes it seem like there has only been one or two studies on it, when there are like 18 that I know of. It makes me suspect of their other findings as well. Longvida has multiple studies run by university labs in Australia, India, US, France, etc. which are not linked via funding to Verdure. I am not saying it's conclusive. However, I am more comfortable with the authors and sources supporting Longvida, than I am of the authors criticizing it.
The fact that Verdure agreed to let us sell it in both bulk and capsules, along with not making us exclusive, sealed the deal. They seem to be comfortable with the efficacy of their product enough to allow us to let people try it back to back with their competition. That's exactly what I am planning on doing too. I want to bring out at least two more of the patented curcumin products, and have them in a trial pack together, along with regular old curcumin. I am just deciding on which to go with.