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Comment · Wed, October 21, 2015 · Ceretropic & Nootropics Depot

Magnesium l-threonate/Magtein: publication bias in its human trials

Original post in this thread

gwern · 45 points

Magnesium l-threonate is a variety of magnesium suggested in a few small animal studies to have better uptake into the brain and hence increased cognitive effects compared to more common forms of magnesium supplements like magnesium citrate. I am interested in magnesium supplementation in general, but magnesium l-threonate is far more expensive than magnesium citrate (likely due to its status as a patented formulation, controlled by AIDP Inc & Magceutics), and animal studies are a thin reed to rely on, so I went looking for human trials. In January 2012, the official Magtein website stated that:

A human study for memory and cognitive function has just started at University of Southern California, Department of Psychology, with a leading expert in cognitive health. It is a double-blind, placebo controlled study with 40 individuals. Preliminary results will be available by mid 2012.

In June 2013, I noted that no publications or results had been posted, and the page now read just:

> For the second study, a double-blind, placebo-controlled human study with…

What they were answering

_MoreNowAgain_ · 1 points

Do you guys sell L-Threonate?

u/MisterYouAreSoDumb · Ceretropic & Nootropics Depot

Not at the moment. The normal suppliers of it are out till next year. We are trying to find more. I just have a shitload of it at our office.

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