Comment · Mon, August 31, 2015 · Ceretropic
Stereochemistry of phenylpiracetam and its methyl derivative: improvement of the pharmacological profile [2015]
What they were answering
Debonaire_Death · 7 points
For those curious in the full text, it can be found through SciHub.
>In conclusion, the obtained data demonstrated that E1R (13a)
is the most active memory enhancing enantiomer of the
5-methyl-substituted phenylpiracetam homolog 13, and its
cognition enhancing activity is higher than that of
(R)-phenylpiracetam. In addition, E1R (13a) did not affect
the locomotor activity in mice. To our knowledge, E1R (13a)
is currently the only piracetam derivative demonstrating
sigma-1 receptor modulating activity and displaying substantial
cognition enhancements linked to a novel drug target.
This is very interesting, indeed! It would seem they have discovered a non-stimulating racetam with the stability of Phenylpiracetam and an even higher memory enhancement potential. Awesome!
And since it doesn't affect dopamine transport, I highly doubt it has any of the issues with tolerance! Friggin sweet!
Are you guys getting on this, /u/MisterYouAreSoDumb?
u/MisterYouAreSoDumb · Ceretropic
I've been on that like white on rice for a little while now. The labs are not cooperating with me, though. They think it is too difficult of a synth to justify. However, I am still working on it.