Comment · Sun, March 22, 2015 · Ceretropic
Anyone tried the new tianeptine sulfate?
Original post in this thread
yallapapi · 27 points
Just ordered this from Ceretropic.. Has anyone tried this that can give a comparison between it and the normal tianeptine? Thx.
What they were answering
striker_321 · 4 points
Based on the graph of effects, it looks like one daily dose of 41mg (3.3x regular dose) Tianeptine Sulfate would get you the same peak blood plasma concentration as the Sodium version (~430 ng/ml), however, it would last much longer, with significant levels still in the blood 12 hours later (~204ng/ml). Keeping the redosing requirement in mind for the Sodium version, one would still not average as high of a plasma level of the drug over that duration with the sulfate form, and a smaller dose later in the day may have to be added to achieve this effect. It would also appear that alcohol would likely need to be completely removed from one's intake during treatment, as the liver would be processing tianeptine constantly. Thoughts?
u/MisterYouAreSoDumb · Ceretropic
You are correct. It's about 40mg once per day to get the same therapeutic benefit of 12.5mg three times per day. I always recommend not drinking alcohol with Tianeptine, since they do not play well together. Since this one lasts longer, the time between dosing and consuming alcohol is going to be longer than with the sodium salt.