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Comment · Thu, March 19, 2015 · Ceretropic

Long-term melatonin administration enhances the antioxidant potential of human plasma maintained even after discontinuation of the treatment. (2010)

What they were answering

hugon2 · 6 points

yes it's awesome indeed. that would be great if someone wrote some comprehensive dosage guide. because it's complicated with melatonin. and IIRC long term usage with higher dosages can cause some sleep isues after discontinuation.

u/MisterYouAreSoDumb · Ceretropic

I've spoken to multiple people that are dependent on it now, after long-term high-dose usage. Also, there are studies delving into dosages, and how plasma levels and wakefulness are affected the day after.

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