Comment · Mon, February 2, 2015 · Ceretropic
Discrepancy of study outcomes and anecdotal evidence - how much of nootropic effect is placebo?
Original post in this thread
Aretus · 20 points
This has bugged me for a while. I have experimented with a lot of different substances in my time - mostly recreative drugs, prescription medications and some - few - nootropics.
What I have found out by reading studies is that the actual scientific evidence for a profound impact of nootropics concerning cognitive enhancement. For the effects of many nootropics there is no valid scientific evidence anyway. But even in the cases where there is a good foundation of studies, the amplitude of the effects is extremely minor. In many cases very promising animal studies are followed up by extremely disappointing results in human testing. I'd like to illustrate what I mean using two nootropics with strong scientific evidence backing them up, piracetam and bacopa monnieri.
Piracetam has shown extremely promising results in animal testing using rats. There are some studies suggesting it has a memory-enhancing effect in healthy people, although the better and more intricately designed the studies are, the less pronounced these effects become, up to a point where many studies suggest that piracetam has no memory-enhancing effects in healthy people at all. On the other hand, its neuroprotecti…
What they were answering
the_first_turd · 1 points
It would be amazing to see some kind of partially crowd-sourced scientific studies, especially on nootropics. I constantly see people on reddit and elsewhere pointing out flaws in the design of studies after they've been conducted and published, so why not use that huge pool of suggestions and knowledge to critique and improve them before they are ever performed? Your combination of running Ceretropic and being heavily active on reddit would make a great setup for something like this.
u/MisterYouAreSoDumb · Ceretropic
That's my plan. I have a lot of really big plans for things in the coming years.