Comment · Tue, January 27, 2015 · Ceretropic
N-Acetyl Semax/Selank(fail)
Original post in this thread
andrewcb88 · 5 points
Have tried both Semax and Selank prior to trying the N-Acetyl versions with no success. I trialed a 10mg vial of Selank first intranasally and it did nothing for me; my doses were around 1mg. Then I decided to order the 120mg vial of Semax. Again nothing. I took this vial until it ran out dosing most the time 4mg 2x a day with my final dose being 16mg single shot sub-q and still nothing.
Fast forward a few months and I decide to try the N-Acetyl versions of these peptides. They came in this past Saturday and I dosed 500mcg sub-q of the Selank first....nothing. Mixed the Selank and Semax together(30mg vials each). Have dosed so far 1mg of each...nothing.....2mg each.....nothing.....and today I decided to do 2mg of each sub-q followed by 2mg of each intranasally......if you guessed nothing than you are correct.
I am jelly towards the people these peptides work for. I am not totally sure why these peptides do not work for me but I assume it has something to do with my prior opiate/speed addiction. Just wanted to throw this out there that these peptides don't work for everyone and I am the perfect example.
I got some Naltrexone left and plan on micro dosing the Naltrexone with the…
What they were answering
andrewcb88 · 1 points
Yeah, most things have no effect on me whatsoever. I think it has to do with structural changes in the reward center. I haven't used opioids, benzos or stimulants for about a year and a half now but from what I understand the downregulation can be permanente or very very long lasting.
What do you think about using micro doses of Naltrexone with these peptides? From my understanding they work on the opioid system in one way or another and a micro dose of Naltrexone will just temporarily block these receptors which will cause them to become more sensitive for a period of time and possibly upregulate for a short period of time(atleast in someone with a normal opioid system).
u/MisterYouAreSoDumb · Ceretropic
It's possible. I'm not sure if the opioid system is directly the cause, though. I am leaning toward a downstream one, like IEG expression. Even so, there is so little data on it. If it is opioid receptor related, then it might help.