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Comment · Fri, December 19, 2014 · Ceretropic

PEH, the greatest anxiolytic you've never heard of that could save lives.

Original post in this thread

Bukujutsu · 81 points

Phenylethylidenehydrazine is a GABA-T inhibitor and a metabolite of the MAOI Nardil, which has shown great efficacy for treating anxiety disorders, higher than even Xanax, and is highly regarded on the largest board for social anxiety: www.socialanxietysupport.com/forum/f30/nardil-the-gold-standard-for-treatment-of-social-anxiety-82297/

A high percentage of people suffer from anxiety disorders, and it is much more prevalent within online communities like this. I myself had the misfortune of being born with a dysfunctional GABAergic system which produced severe irrational anxiety from early childhood, without apparent environmental cause, and has destroyed my life.

The standard medications are generally not suitable for long term use and come with serious adverse side effects, interactions, can rapidly cause strong addiction and severe withdrawals, along with other risks, possibly serious long term disorders. For example, there was this recently: http://www.reddit.com/r/Nootropics/comments/2fztey/anxiety_and_sleeping_pills_linked_to_alzheimers/
I believe this is a far more optimal substance for anxiety disorders.

I researched all other gaba-t inhibitors, which would have been m…

What they were answering

cobue · 3 points

Side Effects:

After the first 6 weeks where you should be on 3 tablets a day is when you will likely start getting side effects. Here is a list of the main side effects I experienced. You may not get them or you may get all of them and more.

Fatigue – I battled with this for a long long time before realising that I wasn't using the medication correctly (another reason to have a doctor on bored) . I had been keeping the dose low to try to avoid the fatigue that would hit me after lunch but what I should have been doing is increasing the dose. The medical literature states that you need to start at 3 per day and increase it fairly rapidly as fast as side effects will permit to at least 60mg (4 tablets) per day and keep it there for a month. This is to totally destroy the MAO in your brain. After you have done this you slowly reduce the medication to as low as 1 tablet every other day which will keep the MAO from building up again (though I have never heard of anybody who has managed to get by on this low a dose).

Blurred vision: I noticed this when I was increasing the dose, it resolved after a few weeks

Urinary retention: If you increase the dose too fast or too high (like I did) you may start to have trouble urinating. This can become so severe that you need to be catheterised. If this is happening to you I suggest you drop back the dose a little for a few weeks and then t…

u/MisterYouAreSoDumb · Ceretropic

Are you talking about Nardil, or Phenylethylidenehydrazine? They are structurally related, but totally different MOAs.

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