Comment · Thu, February 6, 2014 · Ceretropic
What is your thoughts on Cebria?
Original post in this thread
I_Am_NoBody_2 · 2 points
I just saw the commerical for Cebria. It sounds pretty interesting. However at closer glance, its ingredients seem nothing out of the ordinary. What is your thoughts on Cebria?
Information from their website:
* What is Cebria? Cebria is a natural memory improvement supplement that’s said to help improve short term memory and increase ability to retain information. This patented blend of neuropeptides is aimed at rebuilding the “connections between brain cells, stimulating your brain’s natural ability to repair and grow.”
* What are the Cebria ingredients? According to its website, Cebria contains a proprietary blend of nootropics to improve memory loss, including lactose, glutamic acid, lysine, leucine, arginine, asparatic acid, serine, phenylalanine, valine, threonine, tyrosine, isoleucine, histidine, methionine, and tryptophan.
What they were answering
FrigoCoder · 3 points
Seems like made by someone who just discovered the Amino acid article on Wikipedia, by slapping N-PEP-12 together with Whey Protein and a few other stuff that seemed cool.
- Lot of people can have adverse reactions to Glutamate, be it from Glutamine, MSG or anything else. I get extremely irritable on pure Glutamine for example, less so on Whey Protein.
- D-Aspartic Acid encourages testosterone production, which might not be appropriate for women, not sure about the exact effects though. I got irritable when I tried DAA, would need a few more tries, but so far it suggests Glutamate sensitive people don't tolerate this either.
- There are lactose intolerant people as well, and I see no point in including it (unless of course they couldn't separate it from the whey :3)
- There is of course also the problem with Phenylketonurics and Phenylalanine, but they're a special group so I won't mention them here in more detail.
- Anecdotally, people don't like D-Serine because it is too sedative. Go for Sarcosine if the aim is NMDA coagonism.
- Methionine supplementation is not exactly recommended, allegedly it can rate limit one of the pathways used to break down Homocysteine, and was shown to excacerbate Schizophrenia.
- Generally it does not make sense to shove down a bunch of amino acids, because they block each others' absorption. It especially does not make sense to mix Tyrosi…
u/MisterYouAreSoDumb · Ceretropic
It's seems like a very silly mix, and would most likely not lead to any nootropic effect. I would actually expect more adverse effects than positive.
This whole N-PEP-12 thing seems stupid to me. You cannot just take a peptide like cerebrolysin and mix up its amino acid parts into a stew to get the same effects. Absorption, transport, and binding characteristics are going to be totally different.